Mifepristone (also called RU 486) is used to trigger an abortion in the early phase of pregnancy. It can be used until Week 10 in pregnancy (up to 70 days following the day you had your last menstrual cycle). 

Mifepristone blocks the natural substance (progesterone) that is essential for the continuation of your pregnancy. It is usually used together with another medicine called misoprostol.

Mifepristone must not be used if you have a rare abnormal pregnancy that is outside the womb (ectopic pregnancy). It won't result in an abortion, but it could be a problem in that scenario. It can lead to an ectopic pregnancy rupture, leading to severe bleeding.

How do I take mifepristone orally

Go through the Medication Guide that you receive from your physician prior to beginning taking Mifepristone. Make sure to read the guide again whenever you need to. 

If you have questions you should ask your doctor or pharmacist. Take a look and complete the Patient Agreement form supplied by your physician. Contact your doctor if don't understand the use of this medication or are not able to follow the directions. 

Mifepristone is only available through your physician. It's not available in stores selling pharmacies.

It is essential to visit the doctor's office at minimum two times in order to finish the treatment and vital examinations. This procedure is only offered under direct medical supervision at the doctor's office or in a clinic or hospital. Make sure you receive clear directions from your physician on who to contact and what you should do in the event in the event of an emergency.

The doctor could conduct an ultrasound scan to make sure that your pregnancy is not more than 10 weeks old and not in the body (ectopic).

Inject mifepristone into your mouth according to the instructions of your doctor generally in a single dose. After you have taken mifepristone, your doctor will instruct you to wait for 24 to 72 hours after taking a different medication (misoprostol) in the mouth as one dose. 

The medication may not function equally if you use misoprostol before 24 hours following the administration of Mifepristone or less than 48 hours after having taken Mifepristone. Follow your doctor's advice closely. Vaginal bleeding that is heavy does not indicate that your abortion is completed.

Side Effects

Diarrhea, nausea, vomiting or weakness can be experienced. If the effects last for longer than the initial 24 hours following taking the second medication (misoprostol) immediately seek medical attention as they could be indicators of a serious medical condition.

The possibility of cramping and bleeding is expected in this procedure. The signs usually indicate that the drugs are working. But, there are times when you experience bleeding and cramps, 

but still be pregnant. It is important to return for every follow-up visit with your physician. The cramping and nausea may become worse in the 24-hour period following the administration of the second medication (misoprostol). 

Your physician may advise you to take a different medications to ease these symptoms. In the event that any one of these symptoms persist or worsen inform your physician or pharmacist immediately.

Spotting and bleeding can be present for as long as 30 days. It could also be more severe than normal menstrual flow. In a few instances this bleeding may need to be stopped surgically. 

Take immediate medical care when you are bleeding enough to soak two full-size, thick pads every hour for two hours or if you're worried about the amount of bleeding.

Make sure to remember that this medication was given by your physician because they have concluded that the value to you is higher that the chance of having side negative effects. A majority of people who take this medication don't experience severe side effects.

what is its purpose?

Mifepristone is an antidepressant that blocks the hormone progesterone, which is required for a pregnancy to last. Mifepristone, when combined with another medicine , misoprostol can be used to stop the pregnancy after ten weeks of gestation (70 days or less prior to the day that marks the beginning of the last menstrual cycle). The prescribed mifepristone dose regimen is: Day one On day one: 200 mg of mifepristone taken orally, Between 24 and 48 hours after taking mifepristone for 24 to 48 hours: 800 mg of misoprostol, taken by mouth (in the pouch of cheeks) in a place that is suitable for the patient. Between seven and fourteen weeks after taking the mifepristone: check-up with your health care professional

Do you think it is safe to take Mifepristone?

Yes. Mifepristone can be safely used when it is used as directed and prescribed and is in line to the Mifepristone Risk Evaluation and Mitigation Strategies (REMS) program. 

It was FDA approved Mifeprex over 20 years ago, based on an extensive and thorough analysis of the scientific research and evidence, and concluded that it was efficient and safe for the purpose it was intended. Since the year 2016, it can be utilized to treat medical termination of pregnancies for up to 70 days gestation. 

he FDA's regular reviews of the postmarketing information for Mifeprex and its approuvé generic have not found any new safety issues related to the use of Mifepristone for the medically terminated pregnancy up to seventy days of gestation. Like all medications that are approved by the FDA, the FDA remains vigilantly monitoring the safety information postmarketing for Mifepristone to ensure the medical termination of pregnancy.

Why is this medicine being prescribed?

Mifepristone can be used in conjunction together with misoprostol (Cytotec) in order to stop the early stage of pregnancy. Early pregnancy refers to when it's been 70-days or less since your last menstrual cycle began. 

Mifepristone belongs to a class of drugs known as antiprogestational steroids. It blocks the progesterone hormone the substance that your body produces to maintain pregnancy.

Mifepristone also comes in a different form (Korlym) that can be used to treat the symptoms of hyperglycemia (high glucose levels) in those who suffer from Cushing's Syndrome , in which the body produces excessive amounts of cortisol, the hormone. 

The monograph is a brief overview about Mifepristone (Mifeprex) that is utilized in conjunction with other medications to stop the premature pregnancy. If you're using Mifepristone for the treatment of hyperglycemia caused by Cushing's disease, then read the monograph titled Mifepristone (Korlym) which has been written about the product.